HEARING-LOSS IN PAGETS-DISEASE OF BONE - EVIDENCE OF AUDITORY-NERVE INTEGRITY

Auditory brainstem responses (ABRs) were recorded in 64 years with rad iographically confirmed Paget's disease involving the skull. Responses were absent in eight ears, all of which had elevated high pure-tone t hresholds. Auditory brainstem responses were interpreted as normal in 56 ears; none were abnormal. Computed tomography and digital image ana lysis were used to quantify internal auditory canal (IAC) dimensions. The midlength diameter and minimum diameter of the IAC of 68 temporal bones from subjects with Paget's disease were found to have no statist ically significant relation to hearing thresholds. Increased IAC lengt h showed a limited relation to reduced hearing level in pagetic subjec ts, possibly consistent with bossing adjacent to the porus acusticus. Findings support the principle that hearing loss in Paget's disease of bone is generally associated with intact auditory nerve function and also support a cochlear site of lesion.