OXYBUTYNIN ADMINISTRATION DIMINISHES THE HIGH GASTRIC MUSCULAR TONE ASSOCIATED WITH BLADDER RECONSTRUCTION

Oxybutynin has a proved role in correcting uninhibited detrusor contra ctions in the intact and the bowel augmented bladder. Beneficial respo nses to oxybutynin have also been noted after gastrocystoplasty. It ha s been questioned whether this response reflects a selective effect on the bladder segment or whether there is an additional effect on the g astric patch musculature. We report a case of improved function of a p reviously poorly compliant gastric neobladder caused by oxybutynin, th ereby demonstrating a direct action on gastric smooth muscle.