G. Adomian et al., A NONPERTURBATIVE ANALYTICAL SOLUTION OF IMMUNE-RESPONSE WITH TIME-DELAYS AND POSSIBLE GENERALIZATION, Mathematical and computer modelling, 24(10), 1996, pp. 89-96
Mathematical models of the dynamic interaction of immune response with
a population of bacteria, viruses, antigens, or tumor cells have been
modelled as systems of nonlinear differential equations or delay-diff
erential equations. Such models can be solved analytically without res
orting to linearization, perturbation, discretization, or restrictions
on stochasticity, such as Wiener processes or closure approximations,
which change the problem supposedly being solved so the solution is n
ot necessarily physically realistic. With the availability of an analy
tical solution method with the potential to solve more general models,
more attention can be devoted to modelling which may more fully repre
sent the complexity of the interactions involved.