L. Harlan et al., GEOGRAPHIC, AGE, AND RACIAL VARIATION IN THE TREATMENT OF LOCAL REGIONAL CARCINOMA OF THE PROSTATE/, Journal of clinical oncology, 13(1), 1995, pp. 93-100
Purpose: Prostate cancer is one of the most common cancers in men. Inc
idence rates increase with age and are substantially higher in black m
en than white men. This study examines the variations in the use of ra
dical prostatectomy and radiation by geographic area, age, and race. M
aterials and Methods: Data from the National Cancer Institute's Survei
llance, Epidemiology, and End-Results Program (SEER) were used to exam
ine treatment differences. Current treatments generally consist of pro
statectomy, radiation, or careful observation for clinically localized
or regional disease. Results: The age-adjusted proportion of men, age
50 and older, who received radical prostatectomy increased sharply be
tween 1984 and 1991, from 11.0% to 32.3% among men with local/regional
disease. The choice of treatment varied widely by geographic regions.
In 1991, the proportion that received prostatectomy was highest in Ut
ah (47.8%) end lowest in Connecticut (22.5%) among men with localized
and regional disease. The increase in radical prostatectomy was not li
mited to younger men. Although the rates increased for blacks, black m
en had lower age-adjusted rates of prostatectomy than whites in all ye
ars of the study. Conclusion: The SEER data show a clear trend toward
more aggressive treatment, especially prostatectomy. However, the prop
ortion of black men who received prostatectomy was substantially lower
than that of white men and this disparity does not appear to be chang
ing.