A patient with a 7-year history of depression relapsed after self-disc
ontinuation of antidepressant drugs. He was admitted to our hospital a
nd re-administered amoxapine 150 mg. p.o. per day, and further given h
aloperidol 5 mg i.m. or p.o. per day because he was suicidal and excit
ed. One month later, an area of alopecia was found on the back of his
head. Immediately, he received dermatological treatment. The psychotro
pic drugs were continued, but the hair loss was unchanged after one mo
nth. So, haloperidol alone was discontinued. One week later, the hair
loss had stopped and a month later alopecia had virtually disappeared.
We suggest that alopecia areata is associated with haloperidol.