A NEW PROCEDURE FOR THE SYNTHESIS OF 4H-PYRAZOLO[1,5-C][1,3,5]THIADIAZINE-4-THIONES

Authors
VICENTINI CB VERONESE AC GUARNERI M MANFRINI M GIORI P GUCCIONE S
Citation
Cb. Vicentini et al., A NEW PROCEDURE FOR THE SYNTHESIS OF 4H-PYRAZOLO[1,5-C][1,3,5]THIADIAZINE-4-THIONES, Journal of heterocyclic chemistry, 31(6), 1994, pp. 1477-1480
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
31
Issue
6
Year of publication
1994
Pages
1477 - 1480
Database
ISI
SICI code
0022-152X(1994)31:6<1477:ANPFTS>2.0.ZU;2-I
Abstract
Thiation of N-(1-tert-butyl-3-methylpyrazol-5-yl)carboxamides 2 with t he Lawesson reagent afforded the corresponding thiocarboxiamides 3. He ating of 3 in formic acid gave the N-dealkylated thiocarboxamides 4 wh ich were cyclized into 4H-pyrazolo[1,5-c][1,3,5]thiadiazine-4-thiones 5 by treatment with thiophosgene.