SYNTHESIS OF -DIHYDRO-4-OXOPYRIDAZINO[1,6-A]INDOLE-3-CARBOXYLIC ACIDSAND 1,4-DIHYDRO-4-OXOPYRIDO[3',2' 4,5]PYRROLO[1,2-B]-PYRIDAZINE-3-CARBOXYLIC ACIDS AS POTENTIAL ANTIBACTERIAL AGENTS/

Authors
RUXER JM LACHOUX C OUSSET JB TORREGROSA JL MATTIODA G
Citation
Jm. Ruxer et al., SYNTHESIS OF -DIHYDRO-4-OXOPYRIDAZINO[1,6-A]INDOLE-3-CARBOXYLIC ACIDSAND 1,4-DIHYDRO-4-OXOPYRIDO[3',2' 4,5]PYRROLO[1,2-B]-PYRIDAZINE-3-CARBOXYLIC ACIDS AS POTENTIAL ANTIBACTERIAL AGENTS/, Journal of heterocyclic chemistry, 31(6), 1994, pp. 1561-1568
Citations number
3
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
31
Issue
6
Year of publication
1994
Pages
1561 - 1568
Database
ISI
SICI code
0022-152X(1994)31:6<1561:SO-A>2.0.ZU;2-B
Abstract
A few aza analogues of the quinolones have been prepared in the two fa milies of the -dihydro-4-oxopyridazino[1,6-a]indole-3-carboxylic acids and the o[3',2':4,5]pyrrolo[1,2-b]-pyridazine-3-carboxylic acids to c heck their antibacterial potential. One compound 6c shows antibacteria l activities of the level of nalidixic acid and represents a new lead structure differing from the classical quinolones.