FORMATION OF ISOINDOLINE DERIVATIVES FROM O-BROMOACETYLBENZOPHENONES

Authors
NANYA S ISHIDA H BUTSUGAN Y
Citation
S. Nanya et al., FORMATION OF ISOINDOLINE DERIVATIVES FROM O-BROMOACETYLBENZOPHENONES, Journal of heterocyclic chemistry, 31(6), 1994, pp. 1725-1726
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
31
Issue
6
Year of publication
1994
Pages
1725 - 1726
Database
ISI
SICI code
0022-152X(1994)31:6<1725:FOIDFO>2.0.ZU;2-Q
Abstract
o-Dibromoacetylbenzophenone, 2 or o-bromoacetylbenzophenone 3 reacted with aqueous ammonia to produce 3-phenylisoindolin-1-one 5. The reacti on of 3 with methylamine afforded 3-hydroxy-2-methyl-3-phenyl-isoindol in-1-one 4 and 2-methyl-3-phenylisoindolin-1-one 5. Whereas from 2 wit h methylamine only 5 was obtained.