DETERMINATION OF DOUBLY LABELED WATER BY GAS-PHASE FOURIER-TRANSFORM INFRARED-SPECTROSCOPY

Authors
KHALED MA KRUMDIECK CL ONG JL
Citation
Ma. Khaled et al., DETERMINATION OF DOUBLY LABELED WATER BY GAS-PHASE FOURIER-TRANSFORM INFRARED-SPECTROSCOPY, Metabolism, clinical and experimental, 44(1), 1995, pp. 1-3
Citations number
3
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Metabolism, clinical and experimental → ACNP
ISSN journal
00260495
Volume
44
Issue
1
Year of publication
1995
Pages
1 - 3
Database
ISI
SICI code
0026-0495(1995)44:1<1:DODLWB>2.0.ZU;2-9
Abstract
Both H-2 (deuterium) and O-18 (oxygen 18) in isotopically enriched wat er have been detected by gas-phase Fourier transform infrared (FTIR) s pectroscopy at 2,720 and 3,661.8 cm(-1), respectively. A linear relati onship between varying concentrations of each of these isotopes and th eir absorbance at the above frequencies indicates that gas-phase FTIR may provide a rapid and potentially less expensive approach to measure doubly labeled water in biological fluids for the estimation of energ y expenditure and total body water. Copyright (C) 1995 by W.B. Saunder s Company