Ss. Werbel et Kp. Ober, PHEOCHROMOCYTOMA - UPDATE ON DIAGNOSIS, LOCALIZATION, AND MANAGEMENT, The Medical clinics of North America, 79(1), 1995, pp. 131
Pheochromocytoma, although rare, is a potentially life-threatening dis
ease, that if recognized early by the physician, can be managed with m
inimal morbidity. A high degree of suspicion in those patients with ne
w onset hypertension with sudden worsening or development of diabetes
mellitus, or a family history of multiple endocrine neoplasia, the neu
roectodermal tumors, or simple pheochromocytoma should prompt biochemi
cal confirmation. Surgical removal is the only definitive therapy. Add
itionally, lifelong follow-up (yearly, initially) is necessary to dete
ct any signs of benign recurrence or malignancy, since these have been
reported to occur as long as 41 years after the initial surgical rese
ction.