HIGHLY PREFERENTIAL CLEAVAGE OF UNPAIRED GUANINES IN DNA BY A FUNCTIONALIZED SALEN-NICKEL COMPLEX

Authors
ROUTIER S BERNIER JL CATTEAU JP BAILLY C
Citation
S. Routier et al., HIGHLY PREFERENTIAL CLEAVAGE OF UNPAIRED GUANINES IN DNA BY A FUNCTIONALIZED SALEN-NICKEL COMPLEX, Bioorganic & medicinal chemistry letters, 7(1), 1997, pp. 63-66
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
1
Year of publication
1997
Pages
63 - 66
Database
ISI
SICI code
0960-894X(1997)7:1<63:HPCOUG>2.0.ZU;2-0
Abstract
In the presence of oxygen donnor compounds, a functionalized salen-nic kel complex poorly cuts double-stranded DNA but induces strong cleavag es at guanine residues in the single-stranded region of hairpin oligon ucleotides. Copyright (C) 1996 Elsevier Science Ltd