3 CLASSES OF GABAERGIC INTERNEURONS IN NEOCORTEX AND NEOSTRIATUM

We have compared the cellular organization of GABAergic interneurons b etween frontal cortex and neostriatum of rats by immunohistochemistry for calcium-binding proteins, somatostatin and nitric oxide synthase ( NOS). GABAergic interneurons in both neocortex and neostriatum could b e divided into three separate populations containing parvalbumin, soma tostatin, or calretinin. NOS cells were considered to be GABAergic and belong to somatostatin cells in both structures. Distributions of cal bindin D-28k in three classes of interneurons were different among neo cortical layers and neostriatum.