Systemic embolism may originate from cardiac abnormalities or atheroma
tous lesions of the arteries. Whereas ischemic stroke due to emboli ar
ising from the carotid arteries is a well-known phenomenon, the thorac
ic aorta came into consideration recently with the widespread use of t
he transesophageal' echocardiography. We report on three patients who
showed mobile masses moving in the blood stream which originated from
atheromatous plaques in the aortic arch in two and in the descending a
orta in one of them. These mobile structures could only be demonstrate
d by transesophageal echocardiography. All patients had suffered from
recurrent episodes of cerebral, visceral or peripheral embolism, two o
f them despite the fact, that they were receiving long-term anticoagul
ant therapy with coumarins. We discuss clinical implications of this t
hromboembolic syndrome; which should be recognized in the diagnostic e
valuation of systemic embolism.