We explore the complex interplay of clinical discovery and controlled
evaluation, demonstrating how experience in the applied arena provides
invaluable insights and ideas about the complexity of the human condi
tion and of ways to intervene effectively. Case studies have features
that earn them a firm place in psychological research, and to ignore t
heir potential contributions is to limit severely the kind of knowledg
e that can be generated by more systematic modes of inquiry. Some limi
tations of group designs in comparative therapy research are also revi
ewed, again highlighting the importance of idiographic analyses of sin
gle cases. Innovation and creative advancement are most readily nurtur
ed via immersion in clinical/applied work, but at the same time the na
ture of that work is inevitably shaped by theories and hypotheses that
clinicians bring into the applied setting. These abstractions are the
mselves influenced by the clinician's interpretations of data, which i
nterpretations are molded by theoretical and metatheoretical preconcep
tions. In this complex and interactive fashion, clinical innovation is
part of a non-linear network of forces that includes personal biases,
professional allegiances, epistemological assumptions, theoretical pr
eferences, and familiarity with and use of certain bodies of data.