Glaucoma has been recognized as an infrequent but serious complication
following surgery for congenital and acquired cataracts in childhood.
Little is known concerning the influence of factors on the risk of gl
aucoma such as age at surgery, type of cataract, associated ocular abn
ormalities, and type of surgery. We reviewed records of 240 eyes of 15
5 patients on whom cataract surgery had been performed between January
1965 and July 1990 at Children's Hospital, Boston. After excluding th
ose patients who had been followed up less than 5 years after surgery,
and those who had had surgery after the age of 10 years, 125 eyes of
82 patients were included in the study group. We identified 14 eyes of
9 patients that had developed open-angle glaucoma 5.3 to 13.1 years f
ollowing surgery (average 7.4 years). An additional 4 eyes of 3 patien
ts developed angle closure glaucoma, which was diagnosed at 146, 177,
2911, and 2939 days following surgery. A fifth patient developed acute
angle closure 1.7 years following primary cataract surgery and 53 day
s following secondary discission. All but one of the patients who deve
loped glaucoma had cataract surgery at less than 1 year of age. Age at
surgery for the entire study group averaged 1.9 years, and ranged fro
m 25 days to 9.6 years. We conclude that patients having cataract surg
ery before 1 year of age are at the greatest risk of developing postop
erative open-angle glaucoma. Additional increased relative risk was fo
und in eyes with microcornea, congenital rubella syndrome, and poor pu
pillary dilation with 1% cyclopentolate (Cyclogyl). No significant dif
ference was seen among the various surgical methods of cataract remova
l.