Jj. Hoorweg et al., FREE VASCULARIZED JEJUNUM INTERPOSITION FOR PHARYNGOESOPHAGEAL RECONSTRUCTION AFTER TOTAL LARYNGOPHARYNGECTOMY, Clinical otolaryngology and allied sciences, 19(6), 1994, pp. 496-501
The records of 28 patients who underwent free jejunal graft reconstruc
tion after resection for cancer involving the pharynx were analysed. S
even patients had a T3 carcinoma, 15 patients T4 and six patients recu
rrence after laryngectomy. Ten patients had received radiotherapy in t
he past. Post-operatively, 15 patients (54%) had complications and two
patients (7%) died. No significant difference was observed in the com
plication rate between the group that received radiotherapy in the pas
t and those who did not. Nineteen patients received post-operative rad
iotherapy. Nine patients had no radiotherapy on the basis of complete
resection or because of serious complications. For the whole group the
2-year recurrence free period and survival were 42% and 51% respectiv
ely. The post-operative radiotherapy group had a significantly better
survival (73%) and recurrence free period (63%) than the group without
post-operative radiotherapy (0%). Thus, post-operative radiotherapy s
eems indicated irrespective of resection margins.