TREATMENT OF INTRACTABLE GASTROINTESTINAL MANIFESTATIONS OF CHRONIC GRANULOMATOUS-DISEASE WITH CYCLOSPORINE

Authors
ROSH JR TANG HB MAYER L GROISMAN G ABRAHAM SK PRINCE A
Citation
Jr. Rosh et al., TREATMENT OF INTRACTABLE GASTROINTESTINAL MANIFESTATIONS OF CHRONIC GRANULOMATOUS-DISEASE WITH CYCLOSPORINE, The Journal of pediatrics, 126(1), 1995, pp. 143-145
Citations number
15
Categorie Soggetti
Pediatrics
Journal title
The Journal of pediatrics → ACNP
ISSN journal
00223476
Volume
126
Issue
1
Year of publication
1995
Pages
143 - 145
Database
ISI
SICI code
0022-3476(1995)126:1<143:TOIGMO>2.0.ZU;2-H
Abstract
Gastrointestinal manifestations of chronic granulomatous disease of ch ildhood include granulomatous inflammatory bowel disease, Severe colit is and perirectal disease developed in a 12-year-old boy with chronic granulomatous disease while he was receiving interferon gamma therapy, The boy had a deficiency of the 22 kd light chain of the cytochrome b heterodimer. After conventional medical therapy proved to be ineffect ive, a rapid clinical response was obtained to cyclosporine.