VALIDATION OF THE MEDICAL EXPERT-SYSTEM RENOIR

Citation
C. Hernandez et al., VALIDATION OF THE MEDICAL EXPERT-SYSTEM RENOIR, Computers and biomedical research, 27(6), 1994, pp. 456-471
Citations number
25
Categorie Soggetti
Mathematical Methods, Biology & Medicine","Engineering, Biomedical","Computer Science Interdisciplinary Applications
ISSN journal
00104809
Volume
27
Issue
6
Year of publication
1994
Pages
456 - 471
Database
ISI
SICI code
0010-4809(1994)27:6<456:VOTMER>2.0.ZU;2-J
Abstract
RENOIR is an expert system developed to assist the diagnosis of 37 dis eases of connective tissue and inflammatory arthropathies. Precise dia gnosis of rheumatic diseases implies great uncertainty and there is no gold standard with which to compare the expert system output. To over come this problem a set of clinical cases was submitted to RENOIR and its diagnoses were compared with those of clinicians. Medical records of 81 patients with rheumatic diseases were interpreted by RENOIR and by 12 clinicians at three different expertise levels in rheumatology. Distances between the likelihoods of the 37 considered diseases provid ed by clinicians and RENOIR were computed as a disagreement measure. M ahalanobis distance was used to correct the collinearity between the p ossibilities of each pair of diseases. Using the resulting matrices of distances between experts, cluster analyses were carried out to class ify RENOIR among human experts. Greater differences between RENOIR and clinicians than among clinicians themselves were not found. (C) 1994 Academic Press, Inc.