Purpose: The purpose of the study is to report on a 34-year-old woman
with Susac syndrome who presented on two separate occasions with visua
l acuity loss from a recurrent branch retinal artery occlusion and und
erwent hyperbaric oxygen treatment with favorable outcome. Methods: Vi
sual acuity was 20/400 in the left eye and count fingers in the right
eye after separate occlusive events. The patient underwent hyperbaric
oxygen treatment on each occasion of visual acuity loss, The patient s
ubsequently was diagnosed with Susac syndrome (microangiopathy of the
retina, brain, and middle ear). The authors present visual fields, pho
tographs, angiograms, and ancillary tests documenting diagnosis and co
urse of treatment. Results: On each occasion, visual acuity improved t
o 20/25 during and was maintained after hyperbaric oxygen treatment. V
isual fields showed improvement immediately after treatment. Conclusio
n: This is the first report of hyperbaric oxygen treatment for Susac s
yndrome, Dramatic post-treatment visual field and acuity changes sugge
st benefit of treatment. Hyperbaric oxygen treatment can be considered
a treatment option for visual complications of this syndrome. Susac s
yndrome should be included in the differential diagnosis of recurrent
branch retinal artery occlusion.