CLINICAL-PATHOLOGICAL CHANGES IN 2 MARMOSETS WITH WASTING SYNDROME

Two sexually mature marmosets (Callithrix jacchus) showing clinical si gns similar to those seen in wasting marmoset syndrome (weight loss, d ecreased muscle mass, and alopecia) were evaluated for clinical and an atomic pathologic changes. The most prominent clinical pathologic alte rations included macrocytic normochromic anemia, hypoproteinemia, hypo albuminemia, elevated serum aspartate aminotransferase and alkaline ph osphatase levels, and previously unreported changes of thrombocytosis. The principal gross and histopathologic Ending was chronic colitis, w hich appeared to be the most important contributing factor to the deve lopment of wasting syndrome in these marmosets.