Several aspects of congestive heart failure are discussed in the light
of international literature and of recent findings of our group. The
annual incidence of heart failure in elderly subjects, aged greater th
an or equal to 75 y, is 13 to 50/1000, while it is 1.6/1000 in people
aged 45-54 y. The prevalence of heart failure is about 3% in subjects
aged 45-64 y, 6% in subjects aged more than 65 y and 10% in subjects a
ged more than 75 y. These data are confirmed by our population based s
tudy in elderly subjects. The etiology of congestive heart failure is
similar in elderly and middle-aged patients. However, several anatomo-
functional, hormonal and autonomic nervous system changes, typical of
congestive heart failure, occur during physiologic ageing processes al
so. These findings may explain the dramatic evolution of congestive he
art failure in elderly patients. Moreover, some features of the elderl
y - e.g. comorbidity, atypical clinical presentations, loss of autonom
y, increased iatrogen risk should be considered. No specific drugs exi
st for the pharmacologic treatment of heart failure in the elderly, so
that the geriatric specificity in the treatment of heart failure can
be recognized in the art of drug choice and dosage, to obtain the best
results with the least side effects. The multiple etiology of congest
ive heart failure, the comorbidity, the loss of autonomy and the deter
ioration of cognitive functions suggest the need for multidimensioal a
pproach and continuative intervention in elderly patients with heart d
isease, and in particular with congestive heart failure. Further studi
es on disease- and age-related changes are necessary to develop new an
d mort potent strategies lo secure 'successful ageing'. Copyright (C)
1996 Elsevier Science Ireland Ltd