Ja. Rogers et al., EFFECTS OF DIETARY VIRGINIAMYCIN ON PERFORMANCE AND LIVER-ABSCESS INCIDENCE IN FEEDLOT CATTLE, Journal of animal science, 73(1), 1995, pp. 9-20
The effects of dietary virginiamycin level on performance and liver ab
scesses in feedlot cattle were evaluated in seven dose-response studie
s. Steers and heifers were fed finishing diets ranging in energy conte
nt from 1.34 to 1.51 Meal of NEg/kg of DM. In all studies, virginiamyc
in added to the diet improved average daily gain and(or) feed conversi
on, with no substantial effect on dry matter intake. Pooled analyses o
f four studies providing virginiamycin at 11.0, 19.3, and 27.6 mg/kg o
f DM in the complete diet indicated that growth and feed conversion we
re linearly improved (P < .05); feeding 19.3 mg/kg improved these meas
urements by 3.0 and 3.8%, respectively. Overall incidence (score 0 vs
score 1, 2, and 3) and severity (score 0, 1, and 2 vs score 3) of live
r abscesses were reduced (P < .01) by feeding virginiamycin at either
19.3 or 27.6 mg/kg Linear plateau modeling indicated that the effectiv
e dose range for virginiamycin in feedlot diets (DM basis) was 19.3 to
27.3 mg/kg for increasing average daily gain, 13.2 to 19.3 mg/kg for
improving feed conversion, and 16.5 to 19.3 mg/kg for reducing liver a
bscess incidence.