Je. Cook et Jl. Cunningham, THE ASSESSMENT OF FRACTURE-HEALING USING DUAL X-RAY ABSORPTIOMETRY - A FEASIBILITY STUDY USING PHANTOMS, Physics in medicine and biology, 40(1), 1995, pp. 119-136
Tissue substitute materials of water and Perspex for soft tissue and a
luminium and hydroxyapatite for bone have been combined into phantoms
to simulate tibial fractures and have been used to assess the viabilit
y of using dual x-ray absorptiometry to quantitatively measure changes
in bone density during fracture healing. It was found that it was pos
sible to detect small gaps created in the aluminium phantoms to simula
te a tibial fracture down to a gap size of 0.05 mm with the gap orient
ed both parallel and perpendicular to the x-ray beam. The mass and are
a density of small samples of calcium hydroxyapatite were found to be
closely correlated with the values of bone mineral content (r(2) = 0.9
7) and density (r(2) = 0.99) given by the scanner, and low values of b
one mineral content and density, which might be expected around a heal
ing fracture, could be precisely measured. Reproducibility of the resu
lts was found to be good with a coefficient of variation of less than
1.5%.