La. Lyapina et al., ANTITHROMBOTIC AND THROMBOLYTIC ACTIVITY OF THE PLASMINOGEN-ACTIVATORISOLATED FROM THE MONOLAYER-CULTURE CELLS, Izvestia Akademii nauk SSSR. Seria biologiceskaa, (3), 1994, pp. 468-471
Plasminogen activator has been isolated from the culture of pig kidney
cells by gel-filtration on Sephadex G-75. The plasminogen activator (
181.9 MU/200 g body weight) protected the animals against thrombosis h
azard in case of provocation by thromboplastin and exerted a thromboly
tic effect in case of thrombus appearance.