Conservative resection of a second primary lung cancer is desirable bu
t not always feasible. We recently carried out three left pneumonectom
ies for the removal of metachronous primary lung cancers in patients w
ho had previously undergone right upper lobe resection for the treatme
nt of bronchogenic carcinoma. In each patient, the results of pulmonar
y function tests plus the findings from quantitative perfusion lung sc
ans predicted a postpneumonectomy forced expiratory volume in 1 second
of at least 1.00 L. All 3 patients had uncomplicated postoperative co
urses, and were doing satisfactorily at follow-up 2 to 6 months later.
One patient died 5 months after pneumonectomy due to unrelated causes
, another died 8 months after pneumonectomy from infection after resec
tion of a brain metastasis, and the third is doing well 15 months afte
r pneumonectomy. The rarity of previously reported cases suggests that
performing a pneumonectomy after contralateral lobectomy may be consi
dered too radical. Our experience indicates the procedure may be consi
dered if the patient's pulmonary function meets the standard criteria
for pneumonectomy.