Mediastinal parathyroid tissue hyperfunctions in as much as 25% of the
patients with primary hyperparathyroidism, and this may be responsibl
e for causing conventional operative procedures to fail in as much as
one-third of the cases. When lesions prove to not be accessible throug
h a cervical incision, or when a mediastinal adenoma is diagnosed befo
re cervical procedures, median sternotomy and angiographic ablation ha
ve been considered the only options for removal. However, thoracoscopy
has theoretic advantages over both. Two patients underwent successful
thoracoscopic removal of a hyperfunctioning ectopic mediastinal parat
hyroid adenoma and their cases are presented here.