Objective: To study differences in employment and work hours among thr
ee groups of HIV-infected and non-infected individuals. Methods: Data
on 1263 patients seen in five different sites in California were drawn
from the AIDS Time-Oriented Health Outcome Study. Three groups of pat
ients were examined: AIDS patients, HIV-positives without diagnosed AI
DS, and HIV-negatives. The HIV-negative patients were used as a compar
ison group in comparing hours worked by all patients, whether they wor
ked or not; the probability of working, regardless of the number of ho
urs; and work hours only for those patients who worked. Results: Adjus
tment for covariates in a 2-equation econometric model reduced the dif
ference in employment rates between the AIDS patients and the other tw
o groups, suggesting that characteristics other than AIDS status accou
nt, in part, for their low employment rates. After adjustment, we did
not find any statistically significant differences in employment proba
bilities or work hours between the HIV-positive patients without diagn
osed AIDS and the comparison group. However, AIDS patients reported ap
proximately 14 work hours fewer (P<0.0001) and lower probabilities of
employment (P<0.0001) than the HIV-negative comparison group among all
patients with and without jobs. Moreover, among those with jobs, pati
ents with AIDS reported approximately 3 work hours fewer per week (P=0
.0385). No statistically significant differences in work hours were fo
und between HIV-positives without diagnosed AIDS and comparison patien
ts. Conclusion: AIDS patients were less likely to be employed than eit
her of the other groups, but crude, unadjusted unemployment rates exag
gerate the effect of AIDS. For those employed, AIDS patients work only
3 h less per week than either of the other groups.