THE EFFECT OF PROPARGYLIC SUBSTITUTION ON THE ACTIVATION AND AROMATIZATION OF ENEDIYNES

Authors
WITTMAN MD KADOW JF PHAM K LEUNG K MASTALERZ HA VYAS DM ROSE WC SOLOMON W ZEIN N
Citation
Md. Wittman et al., THE EFFECT OF PROPARGYLIC SUBSTITUTION ON THE ACTIVATION AND AROMATIZATION OF ENEDIYNES, Bioorganic & medicinal chemistry letters, 4(24), 1994, pp. 2925-2928
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
4
Issue
24
Year of publication
1994
Pages
2925 - 2928
Database
ISI
SICI code
0960-894X(1994)4:24<2925:TEOPSO>2.0.ZU;2-O
Abstract
The thiol activation and aromatization of bicyclo[7.1.0]enediynes was found to be dependent of the nature of the propargyl substituent. Thes e effects are correlated to antitumor activity.