Eleven algal species collected along the coast of the states of Guerre
ro and Oaxaca, Mexico, were analyzed to detect agglutinating activity
in human blood erythrocytes in A(+), B+ and O+ groups. Aqueous extract
s were prepared and frozen until analysis. Microtitration tests were p
erformed with serial dilutions of algal extract and with a constant vo
lume of human erythrocytes at 2 %. They were left to settle, and after
two hours, observed under a microscope. Out of 15 samples analyzed, 2
0 % showed positive agglutination. The active species were Codium gira
ffa, Hypnea spinella and Ulva lactuca. This is the first report of agg
lutinating activity from Mexican algae, and for Codium giraffa and Hyp
nea spinella.