CALCIUM SIGNALING IN PLATELETS AND OTHER NONEXCITABLE CELLS

Authors
SARGEANT P SAGE SO
Citation
P. Sargeant et So. Sage, CALCIUM SIGNALING IN PLATELETS AND OTHER NONEXCITABLE CELLS, Pharmacology & therapeutics, 64(3), 1994, pp. 395-443
Citations number
478
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Pharmacology & therapeutics → ACNP
ISSN journal
01637258
Volume
64
Issue
3
Year of publication
1994
Pages
395 - 443
Database
ISI
SICI code
0163-7258(1994)64:3<395:CSIPAO>2.0.ZU;2-S
Abstract
By virtue of their biological simplicity and widespread availability, platelets frequently have been used as a model system to study signal transduction. Such studies have revealed that changes in intracellular free calcium concentration are central to platelet functioning. The f ollowing article reviews current concepts of platelet structure and fu nction, with particular emphasis on the mechanisms involved in platele t Ca2+ signalling.