SYNTHESIS, CONFORMATIONAL FLEXIBILITY AND PRELIMINARY COMPLEXATION BEHAVIOR OF ALPHA,ALPHA'-TREHALOSE-BASED MACROCYCLES CONTAINING THIOUREASPACERS

Authors
FERNANDEZ JMG BLANCO JLJ MELLET CO FUENTES J
Citation
Jmg. Fernandez et al., SYNTHESIS, CONFORMATIONAL FLEXIBILITY AND PRELIMINARY COMPLEXATION BEHAVIOR OF ALPHA,ALPHA'-TREHALOSE-BASED MACROCYCLES CONTAINING THIOUREASPACERS, Journal of the Chemical Society, Chemical Communications, (1), 1995, pp. 57-58
Citations number
20
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
1
Year of publication
1995
Pages
57 - 58
Database
ISI
SICI code
0022-4936(1995):1<57:SCFAPC>2.0.ZU;2-N
Abstract
An efficient synthesis of macrocyclic ligands incorporating two alpha, alpha'-trehalose subunits linked through the primary C-6,6' positions by means of 1,3-thiourea spacers is reported; the Z/E configuration of the N-C(=S) bonds is governed by intramolecular hydrogen bonding as w ell as steric factors.