SYNTHESIS OF A HIGHLY FUNCTIONALIZED AB TAXANE RING-SYSTEM - FORMATION OF THE 8-MEMBERED RING BY AN EFFICIENT 8-EXO-TET ALKYLATION OF AN ALPHA-SULFONYL ANION

Authors
CRICH D NATARAJAN S
Citation
D. Crich et S. Natarajan, SYNTHESIS OF A HIGHLY FUNCTIONALIZED AB TAXANE RING-SYSTEM - FORMATION OF THE 8-MEMBERED RING BY AN EFFICIENT 8-EXO-TET ALKYLATION OF AN ALPHA-SULFONYL ANION, Journal of the Chemical Society, Chemical Communications, (1), 1995, pp. 85-86
Citations number
30
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
1
Year of publication
1995
Pages
85 - 86
Database
ISI
SICI code
0022-4936(1995):1<85:SOAHFA>2.0.ZU;2-H
Abstract
An efficient, scalable route to a Taxol A ring synthon has been develo ped; its successful elaboration to a highly functionalized AB system b y means of a novel nucleophilic ring closure is described.