This article reviews 14 multivariate theories of experimental substanc
e use (e.g., alcohol and marijuana use) among adolescents, including t
hose theories that emphasize (a) substance-specific cognitions, (b) so
cial learning processes, (c) commitment to conventional values and att
achment to families, and (d) intrapersonal processes. Important simila
rities and differences among these theories are addressed, as are the
conceptual boundaries of each theory. in an attempt to integrate exist
ing theories, a framework is proposed that organizes their central con
structs into 3 distinct types of influence (viz., social, attitudinal,
and intrapersonal) and 3 distinct levels of influence (viz., proximal
, distal, and ultimate). Implications for future theory development ar
e discussed.