Treadmills are often used in research projects to simulate overground
locomotion, assuming that locomotion is similar on a treadmill and ove
rground. The purpose of this investigation was to determine whether a
treadmill could be used to simulate overground locomotion. Twenty-two
subjects ran on four different surfaces: overground and three treadmil
ls that differed in size and power. The kinematics of the right leg an
d foot were studied using two high-speed Locam cameras (lateral and po
sterior view). The subjects ran in two different shoes at four differe
nt speeds (3.0-6.0 m.s(-1)). The differences in the kinematics between
treadmill and overground running could be divided into systematic and
subject dependent components. Subjects systematically planted their f
eet in a flatter position on the treadmill than overground. Most of th
e lower extremity kinematic variables, however, showed inconsistent tr
ends for individual subjects, depending on the individual subject's ru
nning style, running speed, and shoe/treadmill situation. The differen
ces were substantial. It is not yet understood how the human locomotor
system adapts to a particular treadmill running situation. However, i
t is concluded that individual assessment of running kinematics on a t
readmill for shoe or shoe orthotic assessment may possibly lead to ina
dequate conclusions about overground running.