TRISOMY-5 IN LONG-TERM CULTURES FROM BONE-MARROW OF PATIENTS WITH SOLID TUMORS

Authors
OZISIK YY MORGAN R PEIER A MELONI AM SANDBERG AA
Citation
Yy. Ozisik et al., TRISOMY-5 IN LONG-TERM CULTURES FROM BONE-MARROW OF PATIENTS WITH SOLID TUMORS, Cancer genetics and cytogenetics, 78(2), 1994, pp. 207-209
Citations number
15
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
78
Issue
2
Year of publication
1994
Pages
207 - 209
Database
ISI
SICI code
0165-4608(1994)78:2<207:TILCFB>2.0.ZU;2-Y
Abstract
Long-term cultures of bone marrow from 15 cases diagnosed previously w ith primary solid tumors were analyzed cytogenetically. Of these cases , 10 had normal karyotypes and five had chromosomal abnormalities. Tri somy 5 was found in four cases, three with trisomy 5 as the only chang e and one with trisomy 5 and trisomy 12. These results suggest that tr isomy 5 may be a nonrandom change associated with an in vitro or in vi vo phenomenon.