Jr. Hogenmiller et al., PATTERNS OF PAP-SMEAR SCREENING IN WOMEN DIAGNOSED WITH INVASIVE CERVICAL-CANCER, Journal of gynecologic surgery, 10(4), 1994, pp. 247-253
The purpose of this study was to gather data about the extent and natu
re of the observation that many women with invasive cervical cancer we
re reporting a history of regular Pap smears. A retrospective explorat
ory/descriptive design was used to examine and characterize the Pap sm
ear histories of women with invasive cervical cancer. The study popula
tion consisted of women (n = 102) with invasive cervical cancer who at
tended the study institution over a 3-year period. Forty-seven percent
of 101 evaluable cases had participated in regular Pap smear screenin
g, as defined, yet were diagnosed with invasive cervical cancer. Twent
y-six percent of women were diagnosed at the time of a routine planned
Pap smear, with 64% seeking an appointment because of symptomatology.
Forty-four percent had a biopsy at the time of presentation to their
physician because of an identifiable lesion, as compared with the sequ
ence of abnormal cytology with confirmatory biopsy following. The data
were suggestive of the Pap smear being a less sensitive screening too
l for adenocarcinoma histology. The Pap smear as a screening tool had
made a significant contribution to reducing invasive cervical cancer.
However, as currently used, it has not been the complete answer. Resea
rch is needed to definitively identify the limitations of the Pap smea
r as it pertains to quality control (collection and evaluation) in pra
ctice and ability to detect various cervical histologies, in addition
to how current and new techniques could be incorporated to maximize di
agnosis of preinvasive cervical cancer.