A NOVEL-APPROACH TO FUNCTIONALIZED POLICYCLIC SYSTEMS - SYNTHESIS OF TETRACYCLIC COMPOUNDS BY SEQUENTIAL DIELS-ALDER REACTIONS OF 2-ACYLATED 4H,6H-THIENO[3,4,-C]FURAN 5,5-DIOXIDE
K. Konno et al., A NOVEL-APPROACH TO FUNCTIONALIZED POLICYCLIC SYSTEMS - SYNTHESIS OF TETRACYCLIC COMPOUNDS BY SEQUENTIAL DIELS-ALDER REACTIONS OF 2-ACYLATED 4H,6H-THIENO[3,4,-C]FURAN 5,5-DIOXIDE, Heterocycles, 39(1), 1994, pp. 51-54
The 7-oxa-2,3-dimethylenenorbornene derivative (3), synthesized previo
usly from 4H,6H-thieno[3,4-c]furan 5,5-dioxide (1) through its 2-acyla
ted derivative (2), reacted with a variety of dienophiles to give the
adducts (4), the functionalized tetracyclic compounds, in good to exce
llent yield.