SYNTHESIS OF FLUORINATED ANALOGS OF HEMATOPORPHYRIN .2.

Authors
OMOTE M ANDO A KOYAMA M TAKAGI T KUMADAKI I
Citation
M. Omote et al., SYNTHESIS OF FLUORINATED ANALOGS OF HEMATOPORPHYRIN .2., Heterocycles, 39(1), 1994, pp. 381-384
Citations number
5
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
39
Issue
1
Year of publication
1994
Pages
381 - 384
Database
ISI
SICI code
0385-5414(1994)39:1<381:SOFAOH>2.0.ZU;2-O
Abstract
With the aim of obtaining a porphyrin derivative useful for diagnosis and therapy of cancer, fluorinated analogs of hematoporphyrin, which h ad a trifluorohydroxyethyl group in the place of one of the hydroxyeth yl groups, were synthesized by acetylation of trifluorohydroxyethyldeu teroporphyrin dimethyl esters, followed by reduction of the acetyl gro up.