SYNTHESES OF 2-OXABICYCLO[4.10.0]HEXADEC-1(6)-ENE FROM CYCLODODECANONE

Authors
ZAKHARKIN LI CHURILOVA IM
Citation
Li. Zakharkin et Im. Churilova, SYNTHESES OF 2-OXABICYCLO[4.10.0]HEXADEC-1(6)-ENE FROM CYCLODODECANONE, Russian chemical bulletin, 43(4), 1994, pp. 608-611
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Russian chemical bulletin → ACNP
ISSN journal
10665285
Volume
43
Issue
4
Year of publication
1994
Pages
608 - 611
Database
ISI
SICI code
1066-5285(1994)43:4<608:SO2FC>2.0.ZU;2-L
Abstract
Two methods for the synthesis of 2-oxabicyclo[4.10.0]hexadec-1 (6)-ene from cyclododecanone have been suggested. The most convenient method involves the preparation of 2-(3-tert-butoxypropyl)cyclododecanone by phase-transfer catalyzed alkylation of cyclododecanone with 1-bromo-3- tert-butoxypropane followed by removal of the protecting tert-butyl gr oup and elimination of water.