Cavernous angiomas are vascular malformations affecting any part of th
e central nervous system (CNS). The management of asymptomatic caverno
us angiomas is still debated due to their poorly understood natural hi
story, although more data are now available regarding results of surgi
cal treatment in symptomatic cases. The authors report their surgical
experience with 18 pediatric patients operated on for symptomatic CNS
cavernous angiomas. The children ranged in age from 10 months to 17 ye
ars, without a relevant sex difference. Cavernous angiomas were intrac
ranial in 17 cases: 15 being in the supratentorial compartments and tw
o in the cerebellum. Clinical manifestations were as follows: seizures
in 11 cases, focal neurologic deficits in five, and headache in one.
The 18th case was observed in a girl showing paraparesis in the spinal
subdural-extramedullary space at T-8-T-9 level. Excision of four deep
cerebral lesions was performed after stereotactic localization throug
h non-eloquent cortex. Pathologic confirmation of cavernous angiomas w
as obtained in all patients. Mortality from surgical procedures was ab
sent in this series. The follow-up period ranged from 1 to 16 years. A
ll 11 epileptic patients obtained seizure control; improvement or stab
ilization of neurologic symptoms was observed in the remaining seven p
atients.