A NEW SYNTHETIC ROUTE TO PERFLUOROALKYLIDENE-ALPHA, OMEGA-BISPHOSPHONATES

Authors
NAIR HK BURTON DJ
Citation
Hk. Nair et Dj. Burton, A NEW SYNTHETIC ROUTE TO PERFLUOROALKYLIDENE-ALPHA, OMEGA-BISPHOSPHONATES, Tetrahedron letters, 36(3), 1995, pp. 347-350
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
3
Year of publication
1995
Pages
347 - 350
Database
ISI
SICI code
0040-4039(1995)36:3<347:ANSRTP>2.0.ZU;2-H
Abstract
The UV irradiation of a mixture of (EtO)(2)POP(OEt)(2) and I(CF2)(n)I (n = 3,4, 6) or I(CF2)(n)P(O)(OEt)(2) (n = 1, 2) results in the corres ponding bisphosphonites or mixed phosphonite-phosphonates, respectivel y: which on oxidation by Me(3)COOH afforded the perfluoroalkylidene-al pha,omega-bisphosphonates in 64-77% isolated yields.