2-DIBENZYLAMINOBUTANE-1,4-DIOL - A VERSATILE INTERMEDIATE FOR A CHIROSPECIFIC BETA-AMINO ACID SYNTHESIS

Authors
GMEINER P ORECHER F THOMAS C WEBER K
Citation
P. Gmeiner et al., 2-DIBENZYLAMINOBUTANE-1,4-DIOL - A VERSATILE INTERMEDIATE FOR A CHIROSPECIFIC BETA-AMINO ACID SYNTHESIS, Tetrahedron letters, 36(3), 1995, pp. 381-382
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
3
Year of publication
1995
Pages
381 - 382
Database
ISI
SICI code
0040-4039(1995)36:3<381:2-AVIF>2.0.ZU;2-R
Abstract
Starting from the chiral building block 1, which is readily available from natural aspartic acid, a concise and versatile synthesis of optic ally active beta-amino acids including beta-proline derivatives is rep orted. Regioselective transformations of the 1,4-bis-electrophile 2 ar e facilitated by an anchimeric participation.