SINGLE-STEP STEREOSPECIFIC TRANSFORMATION OF 2-PHENYLTHIO SECONDARY AMIDES INTO (Z)-3-CHLORO-2-PHENYLTHIO ACRYLAMIDES

Authors
MAGUIRE AR MURPHY ME SCHAEFFER M FERGUSON G
Citation
Ar. Maguire et al., SINGLE-STEP STEREOSPECIFIC TRANSFORMATION OF 2-PHENYLTHIO SECONDARY AMIDES INTO (Z)-3-CHLORO-2-PHENYLTHIO ACRYLAMIDES, Tetrahedron letters, 36(3), 1995, pp. 467-470
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
3
Year of publication
1995
Pages
467 - 470
Database
ISI
SICI code
0040-4039(1995)36:3<467:SSTO2S>2.0.ZU;2-3
Abstract
alpha-Phenylthio secondary propanamides la-e are converted stereospeci fically on treatment with NCS to the analogus (%)-alpha-phenylthio-bet a-chloro propenamides 2a-e. Extension to longer chain secondary amide derivatives. 1f-g is also possible, albeit less efficiently and withou t any appreciable stereoselectivity.