BIOTRANSFORMATION OF ALOSETRON - MECHANISM OF HYDANTOIN FORMATION

Authors
KNAGGS AR CABLE KM CANNELL RJP SIDEBOTTOM PJ WELLS GN SUTHERLAND DR
Citation
Ar. Knaggs et al., BIOTRANSFORMATION OF ALOSETRON - MECHANISM OF HYDANTOIN FORMATION, Tetrahedron letters, 36(3), 1995, pp. 477-480
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
3
Year of publication
1995
Pages
477 - 480
Database
ISI
SICI code
0040-4039(1995)36:3<477:BOA-MO>2.0.ZU;2-4
Abstract
The formation of the hydantoin biotransformation product (3) of Aloset ron (1) has been shown to proceed via migration of the tricyclic lacta m moiety and occurs with complete retention of both hydrogens in the C -7' methylene group.