PROTECTION AGAINST HOMOLOGOUS BUT NOT HETEROLOGOUS CHALLENGE INDUCED BY INACTIVATED FELINE IMMUNODEFICIENCY VIRUS-VACCINES

Authors
HOSIE MJ OSBORNE R YAMAMOTO JK NEIL JC JARRETT O
Citation
Mj. Hosie et al., PROTECTION AGAINST HOMOLOGOUS BUT NOT HETEROLOGOUS CHALLENGE INDUCED BY INACTIVATED FELINE IMMUNODEFICIENCY VIRUS-VACCINES, Journal of virology, 69(2), 1995, pp. 1253-1255
Citations number
19
Categorie Soggetti
Virology
Journal title
Journal of virology → ACNP
ISSN journal
0022538X
Volume
69
Issue
2
Year of publication
1995
Pages
1253 - 1255
Database
ISI
SICI code
0022-538X(1995)69:2<1253:PAHBNH>2.0.ZU;2-J
Abstract
Whale inactivated virus vaccines from the FL4 cell line protected agai nst challenge with homologous feline immunodeficiency virus (Petaluma strain) but not against a heterologous FIV isolate (GL-8) which is dis tinct from the Petaluma strain in virus neutralization. Protection was associated with a type-specific neutralizing antibody response and wa s retained when the challenge virus was propagated in an unrelated cel l line.