1. In a one-year follow-up 198 patients on lithium therapy, besides th
eir regular check-ups, were assessed on mood, side-effects and intrace
llular lithium. 2. The authors were not able to find a correlation bet
ween the so called lithium index (i.e. the quotient intracellular lith
ium/plasma lithium) and the mood score. 3. In the group of patients wh
ich used no co-medication at all during the year of the follow-up the
authors also failed to find a correlation between the lithium index an
d some of the clinically most relevant side-effects. However, in that
selected group of ''only-lithium-using patients''-only 29 in all-the a
uthors found a remarkable stability in the index value. 4. So even if
the authors, in fact, rejected the lithium index estimation as a tool
in daily praxis, the authors would once again underline the interestin
g findings about the so-called lithium index.