USE OF POROUS GRAPHITIZED CARBON COLUMN FOR DETERMINING TAXOL IN TAXUS-BACCATA

Porous graphitized carbon columns have been used for the separation an d quantitative determination of the anticancer drug taxol in the bark and foliage of Taxus baccata. Successful separations were achieved usi ng water: dioxane 54:46 v/v eluent. Peak purity tests and the spectra of taxol peaks taken at different retention times indicated that the t axol peak is not entirely homogeneous and probably contains other taxo teres coeluted with the main compound.