LISSENCEPHALY-1 IS ONE OF THE MOST CONSERVED PROTEINS BETWEEN MOUSE AND HUMAN, A SINGLE AMINO-ACID DIFFERENCE IN 410 RESIDUES

Authors
PETERFY M GYURIS T BASU R TAKACS L
Citation
M. Peterfy et al., LISSENCEPHALY-1 IS ONE OF THE MOST CONSERVED PROTEINS BETWEEN MOUSE AND HUMAN, A SINGLE AMINO-ACID DIFFERENCE IN 410 RESIDUES, Gene, 150(2), 1994, pp. 415-416
Citations number
5
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
150
Issue
2
Year of publication
1994
Pages
415 - 416
Database
ISI
SICI code
0378-1119(1994)150:2<415:LIOOTM>2.0.ZU;2-Y
Abstract
The nucleotide (nt) sequence of the LIS-1 cDNA encoding the murine lis sencephaly-1 (LIS-1) protein has been determined. The deduced protein shows a very high degree (99.8%) of homology with human LIS-1, having a single conservative amino acid (aa) change out of 410 aa and is iden tical to a subunit of bovine platelet-activating factor (PAF) acetylhy drolase.