Carpal tunnel syndrome is the most common entrapment neuropathy in the
United States, The diagnosis should be considered for any patient wit
h hand or wrist pain, weakness, or numbness, Changes in sensory conduc
tion velocities across the wrist appear to be the most sensitive elect
rophysiologic indicators of the condition, Treatment of mild cases inv
olves avoiding the precipitating activity, wrist splinting, and local
steroid injections; surgical decompression is often required for moder
ate and severe cases. Overall, prognosis relates directly to the sever
ity of the median nerve injury at diagnosis, the clinical cause, and t
he mode of treatment.