Organic solvents cause injury to lipids of neuronal and glial membrane
s. A well known characteristic of workers exposed to thinner is optic
neuropathy. We decided to look for neurophysiologic signs of visual da
mage in patients identified as thinner abusers. Pattern reversal visua
l evoked potentials was performed on 34 thinner abuser patients and 30
controls. P-100 wave latency was found to be longer on abuser than co
ntrol subjects. Results show the possibility of central alterations on
thinner abusers despite absence of clinical symptoms.